2023
Editorial: Novel perspectives on the NLRP3 inflammasome
Liang Y, Hua KF
Frontiers in immunology · DOI 10.3389/fimmu.2023.1211385 · PMID 37251397
Publications
Publications
Browse recent publications with filters for title, author, journal, and year.
2022 Nov
Excessive IL-10 and IL-18 trigger hemophagocytic lymphohistiocytosis-like hyperinflammation and enhanced myelopoiesis
Tang Y, Xu Q, Luo H, Yan X, Wang G, Hu L, Jin J, Witte DP, Marsh RA, Huang L, Huang G, Zhou J
The Journal of allergy and clinical immunology · DOI 10.1016/j.jaci.2022.06.017 · PMID 35792218
2021 Dec 1
Tumor Microenvironment-Derived R-spondins Enhance Antitumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy
Tang Y, Xu Q, Hu L, Yan X, Feng X, Yokota A, Wang W, Zhan D, Krishnamurthy D, Ochayon DE, Wen L, Huo L, Zeng H, Luo Y, Huang LF, Wunderlich M, Zhang J, Vivier E, Zhou J, Waggoner SN, Huang G
Cancer discovery · DOI 10.1158/2159-8290.CD-20-0833 · PMID 34193438
2021 Aug
Germline variants in UNC13D and AP3B1 are enriched in COVID-19 patients experiencing severe cytokine storms
Luo H, Liu D, Liu W, Wang G, Chen L, Cao Y, Wei J, Xiao M, Liu X, Huang G, Wang W, Zhou J, Wang QF
European journal of human genetics : EJHG · DOI 10.1038/s41431-021-00886-x · PMID 33867526
2021 Jun 28
Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention
Zhu X, Chen Z, Shen W, Huang G, Sedivy JM, Wang H, Ju Z
Signal transduction and targeted therapy · DOI 10.1038/s41392-021-00646-9 · PMID 34176928
2021 Jun
Innate immune responses in RNA viral infection
Xu Q, Tang Y, Huang G
Frontiers of medicine · DOI 10.1007/s11684-020-0776-7 · PMID 33263837
2021 Jun
STAT3 and STAT5B mutations have unique distribution in T-cell large granular lymphocyte proliferations and advanced myeloid neoplasms
Qu S, Jia Y, Wang H, Ai X, Xu Z, Qin T, Pan L, Li B, Huang G, Gale RP, Xiao Z
Leukemia & lymphoma · DOI 10.1080/10428194.2020.1869964 · PMID 33410350
2021 May 14
Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity
Rogawski DS, Deng J, Li H, Miao H, Borkin D, Purohit T, Song J, Chase J, Li S, Ndoj J, Klossowski S, Kim E, Mao F, Zhou B, Ropa J, Krotoska MZ, Jin Z, Ernst P, Feng X, Huang G, Nishioka K, Kelly S, He M, Wen B, Sun D, Muntean A, Dou Y, Maillard I, Cierpicki T, Grembecka J
Nature communications · DOI 10.1038/s41467-021-23152-6 · PMID 33990599
2021 Mar 30
Protein S-nitrosylation regulates proteostasis and viability of hematopoietic stem cell during regeneration
Yi W, Zhang Y, Liu B, Zhou Y, Liao D, Qiao X, Gao D, Xie T, Yao Q, Zhang Y, Qiu Y, Huang G, Chen Z, Chen C, Ju Z
Cell reports · DOI 10.1016/j.celrep.2021.108922 · PMID 33789111
2021 Mar 19
VEXAS syndrome in myelodysplastic syndrome with autoimmune disorder
Huang H, Zhang W, Cai W, Liu J, Wang H, Qin T, Xu Z, Li B, Qu S, Pan L, Huang G, Gale RP, Xiao Z
Experimental hematology & oncology · DOI 10.1186/s40164-021-00217-2 · PMID 33741056
2021 Mar
Molecular and clinical features of myeloid neoplasms with somatic DDX41 mutations
Qu S, Li B, Qin T, Xu Z, Pan L, Hu N, Huang G, Peter Gale R, Xiao Z
British journal of haematology · DOI 10.1111/bjh.16668 · PMID 32307695
2021 Feb
Benzene induces rapid leukemic transformation after prolonged hematotoxicity in a murine model
Zhao J, Sui P, Wu B, Chen A, Lu Y, Hou F, Cheng X, Cui S, Song J, Huang G, Xing C, Wang QF
Leukemia · DOI 10.1038/s41375-020-0894-x · PMID 32503976
2021 Jan 5
Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition
Fan C, Zhao C, Zhang F, Kesarwani M, Tu Z, Cai X, Davis AK, Xu L, Hochstetler CL, Chen X, Guo F, Huang G, Azam M, Tian W, Lu QR, Zheng Y
Proceedings of the National Academy of Sciences of the United States of America · DOI 10.1073/pnas.2020102118 · PMID 33443202
2021
Arsenic Dispensing Powder Promotes Erythropoiesis in Myelodysplastic Syndromes via Downregulation of HIF1A and Upregulation of GATA Factors
Fan T, Feng X, Yokota A, Liu W, Tang Y, Yan X, Xiao H, Wang Y, Deng Z, Zhao P, Wang M, Wang H, Ma R, Hu X, Huang G
The American journal of Chinese medicine · DOI 10.1142/S0192415X2150021X · PMID 33641653
2021 Jan
Dynamics of Blood Viral Load Is Strongly Associated with Clinical Outcomes in Coronavirus Disease 2019 (COVID-19) Patients: A Prospective Cohort Study
Chen L, Wang G, Long X, Hou H, Wei J, Cao Y, Tan J, Liu W, Huang L, Meng F, Huang L, Wang N, Zhao J, Huang G, Sun Z, Wang W, Zhou J
The Journal of molecular diagnostics : JMD · DOI 10.1016/j.jmoldx.2020.10.007 · PMID 33122141
2020 Sep
Elevated serum levels of S100A8/A9 and HMGB1 at hospital admission are correlated with inferior clinical outcomes in COVID-19 patients
Chen L, Long X, Xu Q, Tan J, Wang G, Cao Y, Wei J, Luo H, Zhu H, Huang L, Meng F, Huang L, Wang N, Zhou X, Zhao L, Chen X, Mao Z, Chen C, Li Z, Sun Z, Zhao J, Wang D, Huang G, Wang W, Zhou J
Cellular & molecular immunology · DOI 10.1038/s41423-020-0492-x · PMID 32620787
2020 Aug 14
Severe ineffective erythropoiesis discriminates prognosis in myelodysplastic syndromes: analysis based on 776 patients from a single centre
Huang H, Xu C, Gao J, Li B, Qin T, Xu Z, Ren S, Zhang Y, Jiao M, Qu S, Pan L, Hu N, Liu J, Cai W, Zhang Y, Wu D, Zhang P, Gale RP, Huang G, Zhou J, Shi L, Xiao Z
Blood cancer journal · DOI 10.1038/s41408-020-00349-4 · PMID 32801296
2020 Jul
Ruxolitinib in treatment of severe coronavirus disease 2019 (COVID-19): A multicenter, single-blind, randomized controlled trial
Cao Y, Wei J, Zou L, Jiang T, Wang G, Chen L, Huang L, Meng F, Huang L, Wang N, Zhou X, Luo H, Mao Z, Chen X, Xie J, Liu J, Cheng H, Zhao J, Huang G, Wang W, Zhou J
The Journal of allergy and clinical immunology · DOI 10.1016/j.jaci.2020.05.019 · PMID 32470486
2020 Mar
Mutational features of myelodysplastic syndromes with Auer rods reveal them are more akin to acute myeloid leukemia
Huang H, Qin T, Xu Z, Shi Z, Li B, Pan L, Hu N, Qu S, Huang G, Gale RP, Xiao Z
British journal of haematology · DOI 10.1111/bjh.16326 · PMID 31880320
2020 Feb 29
The Clinical, Molecular, and Mechanistic Basis of RUNX1 Mutations Identified in Hematological Malignancies
Yokota A, Huo L, Lan F, Wu J, Huang G
Molecules and cells · DOI 10.14348/molcells.2019.0252 · PMID 31964134
2020 Feb 29
The Role of RUNX1 in NF1-Related Tumors and Blood Disorders
Na Y, Huang G, Wu J
Molecules and cells · DOI 10.14348/molcells.2019.0295 · PMID 31940719
2020 Feb 3
DNMT3A mutants provide proliferating advantage with augmentation of self-renewal activity in the pathogenesis of AML in KMT2A-PTD-positive leukemic cells
Bera R, Chiu MC, Huang YJ, Huang G, Lee YS, Shih LY
Oncogenesis · DOI 10.1038/s41389-020-0191-6 · PMID 32015320
2020
Autophagy Gene Panel-Based Prognostic Model in Myelodysplastic Syndrome
Wang MJ, Liu WY, Wang XY, Li YM, Xiao HY, Quan RC, Huang G, Hu XM
Frontiers in oncology · DOI 10.3389/fonc.2020.606928 · PMID 33614490
2019 Dec 11
Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y
Nature communications · DOI 10.1038/s41467-019-13542-2 · PMID 31827082
2019 Nov
Prognostic mutations in persons with isolated neutropenia myelodysplastic syndrome
Shi Z, Qin T, Xu Z, Li B, Huang H, Zhang H, Fang L, Pan L, Hu N, Qu S, Huang G, Gale RP, Xiao Z
Leukemia & lymphoma · DOI 10.1080/10428194.2019.1607324 · PMID 31056995