2017 Nov
HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis
Huang R, Hayashi Y, Yan X, Bu J, Wang J, Zhang Y, Zhou Y, Tang Y, Wu L, Xu Z, Liu X, Wang Q, Zhou J, Xiao Z, Bridges JP, Marsh RA, Zhang K, Jordan MB, Li Y, Huang G
Haematologica · DOI 10.3324/haematol.2017.174979 · PMID 28860338
2017 Aug
Myeloid neoplasms with germ line RUNX1 mutation
Hayashi Y, Harada Y, Huang G, Harada H
International journal of hematology · DOI 10.1007/s12185-017-2258-5 · PMID 28534116
2017 May 2
Non-driver mutations in myeloproliferative neoplasm-associated myelofibrosis
Li B, Gale RP, Xu Z, Qin T, Song Z, Zhang P, Bai J, Zhang L, Zhang Y, Liu J, Huang G, Xiao Z
Journal of hematology & oncology · DOI 10.1186/s13045-017-0472-5 · PMID 28464892
2017 Mar
MLF1IP promotes normal erythroid proliferation and is involved in the pathogenesis of polycythemia vera
Feng G, Zhang T, Liu J, Ma X, Li B, Yang L, Zhang Y, Xu Z, Qin T, Zhou J, Huang G, Shi L, Xiao Z
FEBS letters · DOI 10.1002/1873-3468.12587 · PMID 28173615
2017 Jan 3
Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes
Wang J, Ai X, Qin T, Xu Z, Zhang Y, Liu J, Li B, Fang L, Zhang H, Pan L, Hu N, Qu S, Cai W, Ru K, Jia Y, Huang G, Xiao Z
Oncotarget · DOI 10.18632/oncotarget.13688 · PMID 27906673
2017
Covalent Modifications of RUNX Proteins: Structure Affects Function
Blumenthal E, Greenblatt S, Huang G, Ando K, Xu Y, Nimer SD
Advances in experimental medicine and biology · DOI 10.1007/978-981-10-3233-2_3 · PMID 28299649
2017
Unraveling Macrophage Heterogeneity in Erythroblastic Islands
Seu KG, Papoin J, Fessler R, Hom J, Huang G, Mohandas N, Blanc L, Kalfa TA
Frontiers in immunology · DOI 10.3389/fimmu.2017.01140 · PMID 28979259
2016 Dec 9
Bone marrow fibrosis grade is an independent risk factor for overall survival in patients with primary myelofibrosis
Li B, Zhang P, Feng G, Xu Z, Qin T, Zhang Y, Sha Z, Dong D, Zhang H, Fang L, Pan L, Hu N, Qu S, Cai W, Huang G, Xiao Z
Blood cancer journal · DOI 10.1038/bcj.2016.116 · PMID 27935577
2016 Nov 10
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment
Dong L, Yu WM, Zheng H, Loh ML, Bunting ST, Pauly M, Huang G, Zhou M, Broxmeyer HE, Scadden DT, Qu CK
Nature · DOI 10.1038/nature20131 · PMID 27783593
2016 Oct 18
Colony-forming unit cell (CFU-C) assays at diagnosis: CFU-G/M cluster predicts overall survival in myelodysplastic syndrome patients independently of IPSS-R
Li B, Liu J, Qu S, Gale RP, Song Z, Xing R, Liu J, Ren Y, Xu Z, Qin T, Zhang Y, Fang L, Zhang H, Pan L, Hu N, Cai W, Zhang P, Huang G, Xiao Z
Oncotarget · DOI 10.18632/oncotarget.12105 · PMID 27655727
2016 Aug 9
Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation
Link KA, Lin S, Shrestha M, Bowman M, Wunderlich M, Bloomfield CD, Huang G, Mulloy JC
Proceedings of the National Academy of Sciences of the United States of America · DOI 10.1073/pnas.1524225113 · PMID 27457952
2016 Jul
The different prognostic impact of type-1 or type-1 like and type-2 or type-2 like CALR mutations in patients with primary myelofibrosis
Li B, Xu Z, Li Y, Peter Gale R, Song Z, Ai X, Qin T, Zhang Y, Zhang P, Huang G, Xiao Z
American journal of hematology · DOI 10.1002/ajh.24378 · PMID 27059877
2016 May 12
Differential role of Id1 in MLL-AF9-driven leukemia based on cell of origin
Man N, Sun XJ, Tan Y, García-Cao M, Liu F, Cheng G, Hatlen M, Xu H, Shah R, Chastain N, Liu N, Huang G, Zhou Y, Sheng M, Song J, Yang FC, Benezra R, Nimer SD, Wang L
Blood · DOI 10.1182/blood-2015-11-677708 · PMID 26944543
2016 Mar 17
Runx1 contributes to neurofibromatosis type 1 neurofibroma formation
Li H, Zhao X, Yan X, Jessen WJ, Kim MO, Dombi E, Liu PP, Huang G, Wu J
Oncogene · DOI 10.1038/onc.2015.207 · PMID 26073082
2016 Mar 17
SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes
Kim JH, Baddoo MC, Park EY, Stone JK, Park H, Butler TW, Huang G, Yan X, Pauli-Behn F, Myers RM, Tan M, Flemington EK, Lim ST, Ahn EY
Molecular cell · DOI 10.1016/j.molcel.2016.02.024 · PMID 26990989
2016 Mar 1
Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation
Wu J, Keng VW, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, Dombi E, Levy DE, Huang G, Cancelas JA, Stemmer-Rachamimov AO, Spinner RJ, Largaespada DA, Ratner N
Cell reports · DOI 10.1016/j.celrep.2016.01.074 · PMID 26904939
2016 Jan 8
RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity
Chin DW, Sakurai M, Nah GS, Du L, Jacob B, Yokomizo T, Matsumura T, Suda T, Huang G, Fu XY, Ito Y, Nakajima H, Osato M
Blood cancer journal · DOI 10.1038/bcj.2015.105 · PMID 26745853
2016
TET2 mutations were predictive of inferior prognosis in the presence of ASXL1 mutations in patients with chronic myelomonocytic leukemia
Cui Y, Tong H, Du X, Li B, Gale RP, Qin T, Liu J, Xu Z, Zhang Y, Huang G, Jin J, Fang L, Zhang H, Pan L, Hu N, Qu S, Xiao Z
Stem cell investigation · DOI 10.21037/sci.2016.09.04 · PMID 27777939
2015 Aug 21
AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis
Park J, Schlederer M, Schreiber M, Ice R, Merkel O, Bilban M, Hofbauer S, Kim S, Addison J, Zou J, Ji C, Bunting ST, Wang Z, Shoham M, Huang G, Bago-Horvath Z, Gibson LF, Rojanasakul Y, Remick S, Ivanov A, Pugacheva E, Bunting KD, Moriggl R, Kenner L, Tse W
Oncotarget · DOI 10.18632/oncotarget.4136 · PMID 26079538
2015 Jul 30
Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression
Wang L, Man N, Sun XJ, Tan Y, García-Cao M, Liu F, Hatlen M, Xu H, Huang G, Mattlin M, Mehta A, Rampersaud E, Benezra R, Nimer SD
Blood · DOI 10.1182/blood-2015-03-635532 · PMID 26084673
2015 Jul
Posttranslational modifications of RUNX1 as potential anticancer targets
Goyama S, Huang G, Kurokawa M, Mulloy JC
Oncogene · DOI 10.1038/onc.2014.305 · PMID 25263451
2015 May
MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition
Kühn MW, Hadler MJ, Daigle SR, Koche RP, Krivtsov AV, Olhava EJ, Caligiuri MA, Huang G, Bradner JE, Pollock RM, Armstrong SA
Haematologica · DOI 10.3324/haematol.2014.115337 · PMID 25596271
2015 Apr 16
MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia
Roychoudhury J, Clark JP, Gracia-Maldonado G, Unnisa Z, Wunderlich M, Link KA, Dasgupta N, Aronow B, Huang G, Mulloy JC, Kumar AR
Blood · DOI 10.1182/blood-2014-09-599258 · PMID 25740828
2015
A systematic classification of megakaryocytic dysplasia and its impact on prognosis for patients with myelodysplastic syndromes
Feng G, Gale RP, Cui W, Cai W, Huang G, Xu Z, Qin T, Zhang Y, Li B, Fang L, Zhang H, Pan L, Hu N, Qu S, Wang J, Cui Y, Xiao Z
Experimental hematology & oncology · DOI 10.1186/s40164-016-0041-6 · PMID 27127725
2015
Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia
Cui Y, Tong H, Du X, Li B, Gale RP, Qin T, Liu J, Xu Z, Zhang Y, Huang G, Jin J, Fang L, Zhang H, Pan L, Hu N, Qu S, Xiao Z
Experimental hematology & oncology · DOI 10.1186/s40164-015-0009-y · PMID 26019984