Last updated

May 15, 2026

Showing 76-100 of 141 publications

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2017 Nov

HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis

Huang R, Hayashi Y, Yan X, Bu J, Wang J, Zhang Y, Zhou Y, Tang Y, Wu L, Xu Z, Liu X, Wang Q, Zhou J, Xiao Z, Bridges JP, Marsh RA, Zhang K, Jordan MB, Li Y, Huang G

Haematologica · DOI 10.3324/haematol.2017.174979 · PMID 28860338

2017 Aug

Myeloid neoplasms with germ line RUNX1 mutation

Hayashi Y, Harada Y, Huang G, Harada H

International journal of hematology · DOI 10.1007/s12185-017-2258-5 · PMID 28534116

2017 May 2

Non-driver mutations in myeloproliferative neoplasm-associated myelofibrosis

Li B, Gale RP, Xu Z, Qin T, Song Z, Zhang P, Bai J, Zhang L, Zhang Y, Liu J, Huang G, Xiao Z

Journal of hematology & oncology · DOI 10.1186/s13045-017-0472-5 · PMID 28464892

2017 Mar

MLF1IP promotes normal erythroid proliferation and is involved in the pathogenesis of polycythemia vera

Feng G, Zhang T, Liu J, Ma X, Li B, Yang L, Zhang Y, Xu Z, Qin T, Zhou J, Huang G, Shi L, Xiao Z

FEBS letters · DOI 10.1002/1873-3468.12587 · PMID 28173615

2017 Jan 3

Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes

Wang J, Ai X, Qin T, Xu Z, Zhang Y, Liu J, Li B, Fang L, Zhang H, Pan L, Hu N, Qu S, Cai W, Ru K, Jia Y, Huang G, Xiao Z

Oncotarget · DOI 10.18632/oncotarget.13688 · PMID 27906673

2017

Covalent Modifications of RUNX Proteins: Structure Affects Function

Blumenthal E, Greenblatt S, Huang G, Ando K, Xu Y, Nimer SD

Advances in experimental medicine and biology · DOI 10.1007/978-981-10-3233-2_3 · PMID 28299649

2017

Unraveling Macrophage Heterogeneity in Erythroblastic Islands

Seu KG, Papoin J, Fessler R, Hom J, Huang G, Mohandas N, Blanc L, Kalfa TA

Frontiers in immunology · DOI 10.3389/fimmu.2017.01140 · PMID 28979259

2016 Dec 9

Bone marrow fibrosis grade is an independent risk factor for overall survival in patients with primary myelofibrosis

Li B, Zhang P, Feng G, Xu Z, Qin T, Zhang Y, Sha Z, Dong D, Zhang H, Fang L, Pan L, Hu N, Qu S, Cai W, Huang G, Xiao Z

Blood cancer journal · DOI 10.1038/bcj.2016.116 · PMID 27935577

2016 Nov 10

Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment

Dong L, Yu WM, Zheng H, Loh ML, Bunting ST, Pauly M, Huang G, Zhou M, Broxmeyer HE, Scadden DT, Qu CK

Nature · DOI 10.1038/nature20131 · PMID 27783593

2016 Oct 18

Colony-forming unit cell (CFU-C) assays at diagnosis: CFU-G/M cluster predicts overall survival in myelodysplastic syndrome patients independently of IPSS-R

Li B, Liu J, Qu S, Gale RP, Song Z, Xing R, Liu J, Ren Y, Xu Z, Qin T, Zhang Y, Fang L, Zhang H, Pan L, Hu N, Cai W, Zhang P, Huang G, Xiao Z

Oncotarget · DOI 10.18632/oncotarget.12105 · PMID 27655727

2016 Aug 9

Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation

Link KA, Lin S, Shrestha M, Bowman M, Wunderlich M, Bloomfield CD, Huang G, Mulloy JC

Proceedings of the National Academy of Sciences of the United States of America · DOI 10.1073/pnas.1524225113 · PMID 27457952

2016 Jul

The different prognostic impact of type-1 or type-1 like and type-2 or type-2 like CALR mutations in patients with primary myelofibrosis

Li B, Xu Z, Li Y, Peter Gale R, Song Z, Ai X, Qin T, Zhang Y, Zhang P, Huang G, Xiao Z

American journal of hematology · DOI 10.1002/ajh.24378 · PMID 27059877

2016 May 12

Differential role of Id1 in MLL-AF9-driven leukemia based on cell of origin

Man N, Sun XJ, Tan Y, García-Cao M, Liu F, Cheng G, Hatlen M, Xu H, Shah R, Chastain N, Liu N, Huang G, Zhou Y, Sheng M, Song J, Yang FC, Benezra R, Nimer SD, Wang L

Blood · DOI 10.1182/blood-2015-11-677708 · PMID 26944543

2016 Mar 17

Runx1 contributes to neurofibromatosis type 1 neurofibroma formation

Li H, Zhao X, Yan X, Jessen WJ, Kim MO, Dombi E, Liu PP, Huang G, Wu J

Oncogene · DOI 10.1038/onc.2015.207 · PMID 26073082

2016 Mar 17

SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes

Kim JH, Baddoo MC, Park EY, Stone JK, Park H, Butler TW, Huang G, Yan X, Pauli-Behn F, Myers RM, Tan M, Flemington EK, Lim ST, Ahn EY

Molecular cell · DOI 10.1016/j.molcel.2016.02.024 · PMID 26990989

2016 Mar 1

Insertional Mutagenesis Identifies a STAT3/Arid1b/β-catenin Pathway Driving Neurofibroma Initiation

Wu J, Keng VW, Patmore DM, Kendall JJ, Patel AV, Jousma E, Jessen WJ, Choi K, Tschida BR, Silverstein KA, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim MO, Dombi E, Levy DE, Huang G, Cancelas JA, Stemmer-Rachamimov AO, Spinner RJ, Largaespada DA, Ratner N

Cell reports · DOI 10.1016/j.celrep.2016.01.074 · PMID 26904939

2016 Jan 8

RUNX1 haploinsufficiency results in granulocyte colony-stimulating factor hypersensitivity

Chin DW, Sakurai M, Nah GS, Du L, Jacob B, Yokomizo T, Matsumura T, Suda T, Huang G, Fu XY, Ito Y, Nakajima H, Osato M

Blood cancer journal · DOI 10.1038/bcj.2015.105 · PMID 26745853

2016

TET2 mutations were predictive of inferior prognosis in the presence of ASXL1 mutations in patients with chronic myelomonocytic leukemia

Cui Y, Tong H, Du X, Li B, Gale RP, Qin T, Liu J, Xu Z, Zhang Y, Huang G, Jin J, Fang L, Zhang H, Pan L, Hu N, Qu S, Xiao Z

Stem cell investigation · DOI 10.21037/sci.2016.09.04 · PMID 27777939

2015 Aug 21

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis

Park J, Schlederer M, Schreiber M, Ice R, Merkel O, Bilban M, Hofbauer S, Kim S, Addison J, Zou J, Ji C, Bunting ST, Wang Z, Shoham M, Huang G, Bago-Horvath Z, Gibson LF, Rojanasakul Y, Remick S, Ivanov A, Pugacheva E, Bunting KD, Moriggl R, Kenner L, Tse W

Oncotarget · DOI 10.18632/oncotarget.4136 · PMID 26079538

2015 Jul 30

Regulation of AKT signaling by Id1 controls t(8;21) leukemia initiation and progression

Wang L, Man N, Sun XJ, Tan Y, García-Cao M, Liu F, Hatlen M, Xu H, Huang G, Mattlin M, Mehta A, Rampersaud E, Benezra R, Nimer SD

Blood · DOI 10.1182/blood-2015-03-635532 · PMID 26084673

2015 Jul

Posttranslational modifications of RUNX1 as potential anticancer targets

Goyama S, Huang G, Kurokawa M, Mulloy JC

Oncogene · DOI 10.1038/onc.2014.305 · PMID 25263451

2015 May

MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition

Kühn MW, Hadler MJ, Daigle SR, Koche RP, Krivtsov AV, Olhava EJ, Caligiuri MA, Huang G, Bradner JE, Pollock RM, Armstrong SA

Haematologica · DOI 10.3324/haematol.2014.115337 · PMID 25596271

2015 Apr 16

MEIS1 regulates an HLF-oxidative stress axis in MLL-fusion gene leukemia

Roychoudhury J, Clark JP, Gracia-Maldonado G, Unnisa Z, Wunderlich M, Link KA, Dasgupta N, Aronow B, Huang G, Mulloy JC, Kumar AR

Blood · DOI 10.1182/blood-2014-09-599258 · PMID 25740828

2015

A systematic classification of megakaryocytic dysplasia and its impact on prognosis for patients with myelodysplastic syndromes

Feng G, Gale RP, Cui W, Cai W, Huang G, Xu Z, Qin T, Zhang Y, Li B, Fang L, Zhang H, Pan L, Hu N, Qu S, Wang J, Cui Y, Xiao Z

Experimental hematology & oncology · DOI 10.1186/s40164-016-0041-6 · PMID 27127725

2015

Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia

Cui Y, Tong H, Du X, Li B, Gale RP, Qin T, Liu J, Xu Z, Zhang Y, Huang G, Jin J, Fang L, Zhang H, Pan L, Hu N, Qu S, Xiao Z

Experimental hematology & oncology · DOI 10.1186/s40164-015-0009-y · PMID 26019984