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May 15, 2026

Showing 51-75 of 141 publications

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2019 Nov

SETD2 mutations confer chemoresistance in acute myeloid leukemia partly through altered cell cycle checkpoints

Dong Y, Zhao X, Feng X, Zhou Y, Yan X, Zhang Y, Bu J, Zhan D, Hayashi Y, Zhang Y, Xu Z, Huang R, Wang J, Zhao T, Xiao Z, Ju Z, Andreassen PR, Wang QF, Chen W, Huang G

Leukemia · DOI 10.1038/s41375-019-0456-2 · PMID 30967619

2019 Oct

Deletion of a flippase subunit Tmem30a in hematopoietic cells impairs mouse fetal liver erythropoiesis

Yang F, Huang Y, Chen X, Liu L, Liao D, Zhang H, Huang G, Liu W, Zhu X, Wang W, Lobo CA, Yazdanbakhsh K, An X, Ju Z

Haematologica · DOI 10.3324/haematol.2018.203992 · PMID 30819915

2019 Oct

Using circulating tumor DNA to monitor myelodysplastic syndromes status

Zhao P, Qin J, Liu W, Zhu Q, Fan T, Xiao H, Wang J, Huang G, Xiaomei H

Hematological oncology · DOI 10.1002/hon.2649 · PMID 31291480

2019 Aug 1

Identification and transcriptome analysis of erythroblastic island macrophages

Li W, Wang Y, Zhao H, Zhang H, Xu Y, Wang S, Guo X, Huang Y, Zhang S, Han Y, Wu X, Rice CM, Huang G, Gallagher PG, Mendelson A, Yazdanbakhsh K, Liu J, Chen L, An X

Blood · DOI 10.1182/blood.2019000430 · PMID 31101625

2019 Jul

Prognostic impact of red blood cell distribution width in myelodysplastic syndromes

Shi Z, Li B, Huang H, Qin T, Xu Z, Zhang H, Fang L, Pan L, Hu N, Qu S, Huang G, Gale RP, Xiao Z

British journal of haematology · DOI 10.1111/bjh.15830 · PMID 30836422

2019 May

Hypoxia/pseudohypoxia-mediated activation of hypoxia-inducible factor-1α in cancer

Hayashi Y, Yokota A, Harada H, Huang G

Cancer science · DOI 10.1111/cas.13990 · PMID 30844107

2019 Apr

RUNX represses Pmp22 to drive neurofibromagenesis

Hall A, Choi K, Liu W, Rose J, Zhao C, Yu Y, Na Y, Cai Y, Coover RA, Lin Y, Dombi E, Kim M, Levanon D, Groner Y, Boscolo E, Pan D, Liu PP, Lu QR, Ratner N, Huang G, Wu J

Science advances · DOI 10.1126/sciadv.aau8389 · PMID 31032403

2019 Mar

Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally

Huang H, Weng H, Zhou K, Wu T, Zhao BS, Sun M, Chen Z, Deng X, Xiao G, Auer F, Klemm L, Wu H, Zuo Z, Qin X, Dong Y, Zhou Y, Qin H, Tao S, Du J, Liu J, Lu Z, Yin H, Mesquita A, Yuan CL, Hu YC, Sun W, Su R, Dong L, Shen C, Li C, Qing Y, Jiang X, Wu X, Sun M, Guan JL, Qu L, Wei M, Müschen M, Huang G, He C, Yang J, Chen J

Nature · DOI 10.1038/s41586-019-1016-7 · PMID 30867593

2019 Mar

The high NRF2 expression confers chemotherapy resistance partly through up-regulated DUSP1 in myelodysplastic syndromes

Lin P, Ren Y, Yan X, Luo Y, Zhang H, Kesarwani M, Bu J, Zhan D, Zhou Y, Tang Y, Zhu S, Xu W, Zhou X, Mei C, Ma L, Ye L, Hu C, Azam M, Ding W, Jin J, Huang G, Tong H

Haematologica · DOI 10.3324/haematol.2018.197749 · PMID 30262569

2019 Feb

[Consistency Analysis of Gene Mutation Sites of Bone Marrow Tumor DNA and Circulating Tumor DNA in Patients with Myelodysplastic Syndrome]

Zhao P, Zhu QZ, Fan T, Liu WY, Xiao HY, Qin JY, Huang G, Hu XM

Zhongguo shi yan xue ye xue za zhi · DOI 10.7534/j.issn.1009-2137.2019.01.024 · PMID 30738462

2018 Dec 10

A Transcription Factor Addiction in Leukemia Imposed by the MLL Promoter Sequence

Lu B, Klingbeil O, Tarumoto Y, Somerville TDD, Huang YH, Wei Y, Wai DC, Low JKK, Milazzo JP, Wu XS, Cao Z, Yan X, Demerdash OE, Huang G, Mackay JP, Kinney JB, Shi J, Vakoc CR

Cancer cell · DOI 10.1016/j.ccell.2018.10.015 · PMID 30503706

2018 Dec

The usefulness of mutational data on prognosis of myelodysplastic syndromes: alone or incorporated into the IPSS-R?

Li B, Liu J, Xu Z, Qin T, Shi Z, Song Z, Huang H, Fang L, Zhang H, Pan L, Hu N, Qu S, Zhang Y, Huang G, Xiao Z

British journal of haematology · DOI 10.1111/bjh.15036 · PMID 29193004

2018 Nov

Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes

Hayashi Y, Zhang Y, Yokota A, Yan X, Liu J, Choi K, Li B, Sashida G, Peng Y, Xu Z, Huang R, Zhang L, Freudiger GM, Wang J, Dong Y, Zhou Y, Wang J, Wu L, Bu J, Chen A, Zhao X, Sun X, Chetal K, Olsson A, Watanabe M, Romick-Rosendale LE, Harada H, Shih LY, Tse W, Bridges JP, Caligiuri MA, Huang T, Zheng Y, Witte DP, Wang QF, Qu CK, Salomonis N, Grimes HL, Nimer SD, Xiao Z, Huang G

Cancer discovery · DOI 10.1158/2159-8290.CD-17-1203 · PMID 30139811

2018 Oct 23

Defective transcription elongation in a subset of cancers confers immunotherapy resistance

Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, Janssen EM, Komurov K

Nature communications · DOI 10.1038/s41467-018-06810-0 · PMID 30353012

2018 Oct

A novel fusion of PDGFRB to TSC1, an intrinsic suppressor of mTOR-signaling pathway, in a chronic eosinophilic leukemia patient with t(5;9)(q32;q34)

Zhang Y, Qu S, Wang Q, Li J, Xu Z, Qin T, Huang G, Xiao Z

Leukemia & lymphoma · DOI 10.1080/10428194.2018.1427855 · PMID 29384404

2018 Oct

Loss of YTHDF2-mediated m(6)A-dependent mRNA clearance facilitates hematopoietic stem cell regeneration

Wang H, Zuo H, Liu J, Wen F, Gao Y, Zhu X, Liu B, Xiao F, Wang W, Huang G, Shen B, Ju Z

Cell research · DOI 10.1038/s41422-018-0082-y · PMID 30150673

2018 Jul

Setd2 regulates quiescence and differentiation of adult hematopoietic stem cells by restricting RNA polymerase II elongation

Zhou Y, Yan X, Feng X, Bu J, Dong Y, Lin P, Hayashi Y, Huang R, Olsson A, Andreassen PR, Grimes HL, Wang QF, Cheng T, Xiao Z, Jin J, Huang G

Haematologica · DOI 10.3324/haematol.2018.187708 · PMID 29650642

2018 Apr

SETD2-mediated crosstalk between H3K36me3 and H3K79me2 in MLL-rearranged leukemia

Bu J, Chen A, Yan X, He F, Dong Y, Zhou Y, He J, Zhan D, Lin P, Hayashi Y, Sun Y, Zhang Y, Xiao Z, Grimes HL, Wang QF, Huang G

Leukemia · DOI 10.1038/leu.2017.339 · PMID 29249820

2018 Feb 12

SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS

Huang Y, Hale J, Wang Y, Li W, Zhang S, Zhang J, Zhao H, Guo X, Liu J, Yan H, Yazdanbakhsh K, Huang G, Hillyer CD, Mohandas N, Chen L, Sun L, An X

Journal of hematology & oncology · DOI 10.1186/s13045-018-0558-8 · PMID 29433555

2018 Feb

Clinical features and biological implications of different U2AF1 mutation types in myelodysplastic syndromes

Li B, Liu J, Jia Y, Wang J, Xu Z, Qin T, Shi Z, Song Z, Peng S, Huang H, Fang L, Zhang H, Pan L, Hu N, Qu S, Zhang Y, Wu J, Liu N, Ru K, Huang G, Xiao Z

Genes, chromosomes & cancer · DOI 10.1002/gcc.22510 · PMID 29057546

2018 Feb

Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia

Huang L, Liu D, Wang N, Ling S, Tang Y, Wu J, Hao L, Luo H, Hu X, Sheng L, Zhu L, Wang D, Luo Y, Shang Z, Xiao M, Mao X, Zhou K, Cao L, Dong L, Zheng X, Sui P, He J, Mo S, Yan J, Ao Q, Qiu L, Zhou H, Liu Q, Zhang H, Li J, Jin J, Fu L, Zhao W, Chen J, Du X, Qing G, Liu H, Liu X, Huang G, Ma D, Zhou J, Wang QF

Cell research · DOI 10.1038/cr.2017.146 · PMID 29148541

2018 Feb

Whole exome sequencing identifies novel mutations of epigenetic regulators in chemorefractory pediatric acute myeloid leukemia

Zhan D, Zhang Y, Xiao P, Zheng X, Ruan M, Zhang J, Chen A, Zou Y, Chen Y, Huang G, Hu S, Wang QF, Zhu X

Leukemia research · DOI 10.1016/j.leukres.2017.12.001 · PMID 29253671

2018 Jan 15

Thalidomide plus prednisone with or without danazol therapy in myelofibrosis: a retrospective analysis of incidence and durability of anemia response

Luo X, Xu Z, Li B, Qin T, Zhang P, Zhang H, Fang L, Pan L, Hu N, Qu S, Zhang Y, Huang G, Peter Gale R, Xiao Z

Blood cancer journal · DOI 10.1038/s41408-017-0029-4 · PMID 29335406

2018 Jan

Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models

Wang J, Hayashi Y, Yokota A, Xu Z, Zhang Y, Huang R, Yan X, Liu H, Ma L, Azam M, Bridges JP, Cancelas JA, Kalfa TA, An X, Xiao Z, Huang G

Haematologica · DOI 10.3324/haematol.2017.172775 · PMID 29051279

2017 Dec 21

Aggressive NK-cell leukemia: clinical subtypes, molecular features, and treatment outcomes

Tang YT, Wang D, Luo H, Xiao M, Zhou HS, Liu D, Ling SP, Wang N, Hu XL, Luo Y, Mao X, Ao QL, Huang J, Zhang W, Sheng LS, Zhu LJ, Shang Z, Gao LL, Zhang PL, Zhou M, Zhou KG, Qiu LG, Liu QF, Zhang HY, Li JY, Jin J, Fu L, Zhao WL, Chen JP, Du X, Huang G, Wang QF, Zhou JF, Huang L

Blood cancer journal · DOI 10.1038/s41408-017-0021-z · PMID 29263371